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Brand name: Tamiflu

Generic name: Oseltamivir

 

Why is Oseltamivir prescribed?

Oseltamivir speeds recovery from the flu. When started during the first 2 days of the illness, Oseltamivir hastens improvement by at least a day. It also can prevent the flu if treatment is started within 2 days after exposure to a flu victim. Oseltamivir is one of a new class of antiviral drugs called neuraminidase inhibitors.

As the flu virus takes hold in the body, it forms new copies of itself and spreads from cell to cell. Neuraminidase inhibitors fight the virus by preventing the release of new copies from infected cells. The other drug in this class, Relenza, is taken by inhalation. Oseltamivir is taken in liquid or capsule form.

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Most important fact about Oseltamivir

Oseltamivir can prevent the flu as long as you continue taking Oseltamivir, but getting a yearly flu shot is still the best way of avoiding the disease entirely. For older adults, those in high-risk situations such as health-care work, and people with an immune deficiency or respiratory disease, vaccination remains a must.

How should you take Oseltamivir?

To provide any benefit, Oseltamivir must be started within two days of the onset of symptoms, or exposure to the flu. If you have the flu, continue taking it twice daily for 5 days, even if you start to feel better. To prevent the flu, take it once a day for at least 7 days. Protection lasts as long as you take the drug.

If Oseltamivir upsets your stomach, try taking it with food. Shake the liquid suspension before each use.

If you miss a dose of Oseltamivir

Take it as soon as possible. If it is within two hours of your next dose, skip the missed dose and go back to your regular schedule.

Storage instructions for Oseltamivir

Store at room temperature. Keep the blister package dry. Use the liquid suspension within 10 days. It should be refrigerated, but do not freeze.

What side effects may occur when taking Oseltamivir?

Most problems noted during tests of Oseltamivir were indistinguishable from the symptoms of flu. Here are the reactions that showed up more frequently in patients taking the drug.

* More common side effects may include:
Abdominal pain, asthma, bronchitis, cough, diarrhea, ear infection, fatigue, headache, insomnia, nausea, nosebleed, vertigo, vomiting

Why should Oseltamivir not be prescribed?

If Oseltamivir gives you an allergic reaction, avoid it in the future.

Special warnings about Oseltamivir

If you have kidney disease, the doctor may have to cut your daily dose of Oseltamivir in half.

The effectiveness of Oseltamivir has not been established for people with weakened immune systems. The drug has not been studied in people with liver disease.

Oseltamivir works only on the flu virus. It won't stop bacterial infections that may have flu-like symptoms or bacterial infections that may develop while you have the flu. If your symptoms persist, check with your doctor.

Possible food and drug interactions when taking Oseltamivir

No interactions have been reported.

Special information on Oseltamivir if you are pregnant or breastfeeding

It is not known whether Oseltamivir is completely safe during pregnancy. If you are pregnant or plan to become pregnant, inform your doctor before taking this medication. Oseltamivir may appear in breast milk and could affect a nursing infant. Taking it while breastfeeding is usually not recommended.

Recommended dosages of Oseltamivir

ADULTS AND CHILDREN 13 AND OLDER

Treatment of Influenza

The usual dosage is 75 milligrams taken twice daily (morning and evening) for 5 days. If you have kidney disease, take a 75-milligram dose once a day.

Prevention of Influenza

The usual dosage is 75 milligrams taken once a day for at least 7 days. If there is a general outbreak of the flu in your community, your doctor may recommend that you continue taking this medication for up to 6 weeks. If you have kidney disease, take a 75-milligram capsule every other day, or 30 milligrams of liquid once a day.

CHILDREN 1 TO 12

Treatment of Influenza

Doses should be given twice daily for 5 days using the dispenser that comes with the liquid suspension. Each dose is determined by the child's weight:

Under 33 pounds: 30 milligrams

33 to 55 pounds: 45 milligrams

51 to 88 pounds: 60 milligrams

Over 88 pounds: 75 milligrams

Oseltamivir should not be used to treat the flu in children under 1 year old.

Prevention of Influenza

Oseltamivir's ability to prevent the flu in children under age 13 has not been established.

Overdosage with Oseltamivir

High doses of Oseltamivir can cause nausea and vomiting. As with any medication, if you suspect an overdose, seek emergency medical treatment immediately.

 

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